Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates.

نویسندگان

  • Inna Chmelnitsky
  • Shiri Navon-Venezia
  • Jacob Strahilevitz
  • Yehuda Carmeli
چکیده

Fourteen out of 16 carbapenem-resistant quinolone-susceptible Enterobacter cloacae isolates were found to carry qnrB2 and bla(KPC-2) genes encoded on the same plasmid. One isolate also carried the aac(6')-Ib-cr gene. Coexistence of quinolone resistance determinants and bla(KPC-2) on the same plasmid in quinolone-susceptible E. cloacae isolates may have important clinical implications.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 52 8  شماره 

صفحات  -

تاریخ انتشار 2008